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pentobarbital will decrease the extent or impact of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Strong or moderate CYP3A4 inducers may well enhance charge of diazepam elimination; for that reason, efficacy of diazepam can be lowered.pentobarbital increases effects of ifosfamide by influencing hepatic